List of all Publications Google Scholar
2025
FGA139, a Novel Cysteine Protease Inhibitor, Exhibits Anti-Inflammatory and Neuroprotective Activity and Reveals Microglial Modulation via Multi-Omics Profiling. A. Canseco-Rodriguez, FV Gonzalez, AM Sanchez-Perez*. BioRiXV 2025
Ultraviolet Ozone Pretreatment Enhances Selective PETase Biodegradation of Textiles Compared to Sunlight and Alkali Treatments. Sariah Narcizo, Antonio Guerrero*, Ana Maria Sanchez-Perez* . ChemBioChem 2025. accepted preprint. http://dx.doi.org/10.1002/cbic.202500004.
Abscisic Acid rescues behavior in adult female mice in Attention Deficit Disorder with Hyperactivity model of dopamine depletion by regulating microglia and vesicular GABA transporter. M Meseguer-Beltrán, S Sánchez-Sarasúa, N Kerekes, M Landry, M Real-López, A M Sánchez-Pérez*. J. of Neuroimmune Pharmacology. 2025. Apr 16;20(1):39. doi: 10.1007/s11481-025-10186-6.
Two- and Three-Dimensional In Vitro Models of Parkinson’s and Alzheimer’s Diseases: State-of-the-Art and Applications. C.Solana-Manrique, AM Sanchez-Perez, N Paricio, S. Muñoz. Int. J. Mol. Sci. 2025, 26(2), 620; https://doi.org/10.3390/ijms26020620
2024
Abscisic Acid, an evolutionarily conserved hormone: Biosynthesis, therapeutic and diagnostic applications in mammals. Amir Gharib, Carlee Marquez, María Meseguer-Beltrán, Sandra Sánchez-Sarasua*, Ana M Sánchez-Pérez*. 2024. Biological Pharmacology. Sep 7:229:116521. Online ahead of print. doi: https://doi.org/10.1016/j.bcp.2024.116521.
Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-based Multitarget Small Molecules. Toledano-Pinedo, Mireia; et al. 2024. J of Medicinal Chemistry, Sep 26;67(18):16533-16555. doi: https://doi.org/10.1021/acs.jmedchem.4c01367
Profiling Cysteine Proteases Activities in Neuroinflammatory Cells. Laura Agost-Beltrán, Ania Canseco-Rodriguez, Tanja Schirmeister, Santiago Rodríguez, Ana María Sánchez-Pérez,* and Florenci V. González,*. 2024 ChemMedChem. 0ct. doi https://doi.org/10.1002/cmdc.202400520
Comparative efficacy of transcraneal magnetic stimulation protocols on schizophrenia symptoms: a systematic review. Teresa Santamaría-Rubio, Matías Real-Lopez, Ana María Sanchez-Perez*. EJPSY under review
2023
ABA Supplementation Rescues IRS2 and BDNF mRNA levels in a Triple-Transgenic Mice Model of Alzheimer’s Disease. Laryssa Alves-Borba, Verónica Espinosa-Fernández, Ania Canseco-Rodríguez and Ana María Sánchez-Pérez*. Journal of Alzheimer´s Disease Reports. 2023 7 (1); 1007 doi 10.3233/ADR-230056
Opening for new Special Issue “Targeting Neuroinflammation and Insulin Resistance for a Healthy Brain: Prevention and Treatment of Neurological and Psychiatric Disorders“ Guest editors Sandra Sánchez Sarasúa and Ana Maria Sanchez-Pérez.
Targeting neuroinflammation with Abscisic Acid reduces pain sensitivity in females and hyperactivity in males of an ADHD mice model. Meseguer-Beltrán, Maria; Sánchez-Sarasúa, Sandra; Landry, Marc; Kerekes, Nóra; Sánchez-Pérez, Ana María*. Cells 2023 12 (3): 465 https://doi.org/10.3390/cells12030465
2022
Accelerated PET enzymatic degradation by room temperature alkali pre-treatment for reduced polymer crystallinity. Sariah Giraldo-Narcizo, Nihal Guenani, Ana María Sánchez-Pérez*, and Antonio Guerrero* ChemBioChem 2022 https://doi.org/10.1002/cbic.202200503
Long non-coding RNAs, extracellular vesicles and inflammation in Alzheimer’s disease. Ania Canseco-Rodríguez, Valeria Masola, Vicenza Aliperti, Maria Meseguer-Beltran, Aldo Donizetti, Ana María Sanchez-Perez*. Int. J. Mol. Sci. 2022, 23, 13171. Topical Collection: Feature Papers in Molecular Genetics and Genomics https://doi.org/10.3390/ijms232113171
Probiotics treatment can improve cognition in patients with Mild Cognitive Impairment. A Systematic Review. Sofía Sánchez de Lara-Sánchez, Ana María Sánchez-Pérez*. Journal of Alzheimer´s Disease. J Alzheimers Dis 2022;89(4):1173-1191. doi.org/10.3233/JAD-220615.
Prediction of Alzheimer’s Disease by a Novel Image-Based Representation of Gene Expression. Habil Kalkan*,Umit Murat Akkaya, Güldal Inal-Gültekin and Ana Maria Sanchez-Perez*. Genes. 2022, 13(8), 1406. Special Issue: Genetics of Alzheimer’s Disease: Clues for Early Diagnosis and Intervention. https://doi.org/10.3390/genes13081406
IRS1 expression in hippocampus is age-dependent and is required for mature spine maintenance and neuritogenesis. Sandra Sánchez-Sarasúa, María Meseguer-Beltrán, Cristina García-Díaz, Maria Teresa Beltrán-Bretones, Nisrin ElMlili, Ana María Sánchez-Pérez*. Molecular and Cellular Neuroscience 2022. 118: 103693. Special Issue: Cytoskeleton and Signaling Pathways: Insights into Neural Cell Development and Disease. doi.org/10.1016/j.mcn.2021.103693
2021
Neuroinflammation as a possible link between attention-deficit/hyperactivity disorder (ADHD) and pain. Nora Kerekes; Ana M Sánchez-Perez, Marc Landry. Medical Hypothesis 2021 (157:110717). doi.org/10.1016/j.mehy.2021.110717
AAV delivery of shRNA against IRS1 in GABAergic neurons in rat hippocampus impairs spatial memory in females and male rats. Sandra Sánchez-Sarasúa, Alberto Ribes-Navarro, María Teresa Beltran-Betrones, Ana M. Sánchez-Pérez* Brain Structure and Function. 2021 Jan;226(1):163-178. doi: 10.1007/s00429-020-02155-x
Adolescent binge-ethanol accelerates cognitive impairment and β-amyloid production and dysregulates endocannabinoid signaling in the hippocampus of APP/PSE mice. Ledesma JC, Rodríguez-Arias M, Gavito AL, Sánchez-Pérez AM, Viña J, Medina Vera D, Rodríguez de Fonseca F, Miñarro J. Addict Biol. 2021 Jan 26(1):e12883. doi: 10.1111/adb.12883 [Epub ahead of print 2020]
2020
Can we treat neuroinflammation in Alzheimer´s Disease? Sandra Sánchez-Sarasúa, Iván Fernández-Pérez, Verónica Espinosa-Fernández, Ana María Sánchez-Pérez* and JCLedesma* Int. J. Mol. Sci. 2020, 21, 8751; doi:10.3390/ijms21228751
Design, Synthesis and Evaluation of Fluorescent Analogues of Abscisic Acid Florenci V. González* Lledó Bou-Iserte, Borja Miguel-López, Sergio de la Hoz-Rodríguez, Christian Kersten, Sandra Sánchez-Sarasúa, Verónica Espinosa-Fernández, and Ana María Sánchez-Pérez* ChemistrySelect 2020, 5: 1-6 doi.org/10.1002/slct.202002294
Abscisic acid, a promising therapeutic molecule to prevent Alzheimer’s and neurodegenerative diseases. Sanchez-Perez AM. Neural Regen Res. 2020 Jun;15(6):1035-1036. doi: 10.4103/1673-5374.270307.
2019
Early intervention with ABA prevents neuroinflammation and memory impairment in a triple transgenic mice model of Alzheimer´s disease. Verónica Espinosa-Fernández, Aroa Mañas-Ojeda, Mar Pacheco-Herrero, Ernestina Castro-Salazar, Francisco Ros-Bernal, Ana María Sánchez-Pérez*. Behav Brain Res. 2019 Nov18;374:112106. doi:10.1016/j.bbr.2019.112106.
Abscisic Acid supplementation rescues high-fat diet-induced alterations in hippocampal inflammation and IRSs expression. Alberto Ribes-Navarro, Mariam Atef, Sandra Sánchez-Sarasúa, María Teresa Beltrán-Bretones, Francisco Olucha-Bordonau, Ana María Sánchez-Pérez* Mol Neurobiol. 2019 Jan;56(1):454-464. doi: 10.1007/s12035-018-1091-z.
Central relaxin-3 receptor (RXFP3) activation impairs social recognition and modulates ERK-phosphorylation in specific GABAergic amygdala neurons, Hector Albert-Gasco, Sandra Sanchez-Sarasua, Sherie Ma, Cristina García-Díaz, Andrew L. Gundlach, Ana M. Sanchez-Perez*, FE. Olucha-Bordonau*. Brain Struct Funct. 2019 Jan;224(1):453-469. doi: 10.1007/s00429-018-1763-5